What peptides are

Peptides are short chains of amino acids that act as signaling molecules in the body. Insulin is a peptide. So is oxytocin. So are many hormones. In a therapeutic context, the term usually refers to a smaller set of compounds used for specific clinical indications — some FDA-approved, some compounded, some investigational.

The peptide space has been aggressively marketed, and much of that marketing runs ahead of the evidence. This guide focuses on the peptide and micronutrient protocols our licensed providers may consider as part of the Longevity program, and why.

Sermorelin

Sermorelin is a growth hormone–releasing hormone analog. It stimulates the body’s own growth hormone release rather than replacing it directly. A licensed provider may consider it for adults with documented low IGF-1 and associated symptoms (reduced recovery, poor sleep quality, altered body composition) after reviewing labs and medical history.

Evidence is moderate and indication-specific. We do not use sermorelin as a generic “anti-aging” injection without a specific clinical rationale.

BPC-157

Popularized for tissue healing and gut repair. The mechanism is plausible, and animal data is promising. Human clinical trial data is limited. It is not FDA-approved, and it is currently on the FDA’s list of substances that cannot be legally compounded. We do not offer BPC-157 given the current regulatory status.

Semaglutide and tirzepatide

These are peptides (GLP-1 receptor agonists) and are covered in detail in our GLP-1 article. FDA-approved, well-studied, and part of standard weight management practice.

Melanotan II and other tanning peptides

Not recommended. Unregulated, associated with atypical mole growth and other risks. We do not offer them.

Thymosin alpha-1

Immune-modulating peptide, approved in some countries for viral hepatitis. Currently not FDA-approved and cannot be legally compounded in the US as of recent FDA guidance. We do not offer.

What good peptide therapy looks like

• A specific clinical indication, not a generic wellness label
• Baseline labs relevant to the intended peptide
• Provider-supervised dosing from a licensed compounding pharmacy or FDA-approved source
• Follow-up monitoring for effect and side effects
• Willingness to stop when the therapy isn’t producing meaningful benefit

What bad peptide therapy looks like

• Peptides sold as research chemicals from unregulated sources
• Marketing that makes sweeping promises about youth or outcomes
• “Stacks” of many peptides combined without a clear indication for each
• No baseline diagnostics or ongoing monitoring

Next steps

Every treatment decision is made by a licensed medical provider after reviewing your consultation, history, and any required labs. If a peptide protocol is not appropriate for you, your provider will tell you. Book a consultation to get started.