HORMONES

DHEA-Sulfate

Also known as DHEA-S

What it is

DHEA-S is an adrenal androgen precursor. The body converts it to testosterone and estrogen in peripheral tissues.

Why it matters

DHEA-S declines with age and can inform decisions about adrenal reserve, mood, and libido in men and women. It is not a first-line hormone marker but adds context to a full panel.

Range GPLX watches for

DHEA-S ranges vary by age and sex. GPLX watches for age-appropriate values in symptomatic patients. Interpretation belongs with your physician.

This educational range is not a personal diagnostic threshold. Your physician interprets your result in context of your full biomarker panel, medications, symptoms, and history.

What abnormal values can suggest

If low

A low DHEA-S value can suggest adrenal insufficiency, chronic stress, aging, or steroid use.

If high

A high DHEA-S value can suggest PCOS in women, adrenal hyperplasia, or, rarely, an adrenal tumor.

This marker is reviewed when clinically appropriate as part of physician-directed labs. Membership is $39.99/month; consultation is $30.

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